Western blot
0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human Live| Product Name | Rabbit anti-NARF polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DKFZp434G0420, FLJ10067, IOP2 |
| Immunogen | The immunogen for anti-NARF antibody: synthetic peptide directed towards the middle region of human NARF |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineHorseHumanMousePigRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | NARF |
|---|---|
| Gene Synonyms | DKFZp434G0420 FLJ10067 IOP2 |
| Gene Full Name | Nuclear prelamin A recognition factor |
| Gene Summary | Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A. NARF binds to the prenylated prelamin A carboxyl-terminal tail domain. It may be a component of a prelamin A endoprotease complex. NARF is located in the nucleus, where it partially colocalizes with the nuclear lamina. It shares limited sequence similarity with iron-only bacterial hydrogenases. |
| Alternative Names | DKFZp434G0420 FLJ10067 IOP2 |
| Molecular Weight(MW) | 45kDa |
| Sequence | 397 amino acids |
| Entrez Gene | 26502 |
|---|---|
| SwissProt ID | B3KPX2 |
| Protein Accession | NP_001033707 |
Western blot
0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human Live| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
