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Rabbit anti-LOXL1 polyclonal antibody - middle region

Catalog Number:OM115796
OM115796
Discount Price
OM115796-100ul
1~2 Week
100ul
OM115796-50ul
50ul
OM115796-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-LOXL1 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias LOL, LOXL
Immunogen The immunogen for anti-LOXL1 antibody: synthetic peptide directed towards the middle region of human LOXL1
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineGuinea PigHorseHumanMousePigRabbitRatZebra Fish
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol LOXL1
Gene Synonyms LOL
LOXL
Gene Full Name Lysyl oxidase-like 1
Gene Summary LOXL1 is a member of the lysyl oxidase family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alternative Names LOL
LOXL
Molecular Weight(MW) 53kDa
Sequence 574 amino acids
Database Links
Entrez Gene 4016
SwissProt ID Q08397
Protein Accession NP_005567
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human Lung
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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