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Rabbit anti-PSMB1 polyclonal antibody - middle region

Catalog Number:OM116648
OM116648
Discount Price
OM116648-100ul
1~2 Week
100ul
OM116648-50ul
50ul
OM116648-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-PSMB1 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias FLJ25321, HC5, KIAA1838, PMSB1, PSC5
Immunogen The immunogen for anti-PSMB1 antibody: synthetic peptide directed towards the middle region of human PSMB1
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogHumanMouseRatZebra Fish
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol PSMB1
Gene Synonyms FLJ25321
HC5
KIAA1838
PMSB1
PSC5
Gene Full Name Proteasome (prosome, macropain) subunit, beta type, 1
Gene Summary The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB1 is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alternative Names FLJ25321
HC5
KIAA1838
PMSB1
PSC5
Molecular Weight(MW) 26kDa
Sequence 241 amino acids
Database Links
Entrez Gene 5689
SwissProt ID P20618
Protein Accession NP_002784
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 721_B cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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