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Rabbit anti-ERCC8 polyclonal antibody - middle region

Catalog Number:OM117433
OM117433
Discount Price
OM117433-100ul
1~2 Week
100ul
OM117433-50ul
50ul
OM117433-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-ERCC8 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias CKN1, CSA
Immunogen The immunogen for anti-ERCC8 antibody: synthetic peptide directed towards the middle region of human ERCC8
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogHorseHumanMouseRabbitRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol ERCC8
Gene Synonyms CKN1
CSA
Gene Full Name Excision repair cross-complementing rodent repair deficiency, complementation group 8
Gene Summary ERCC8 is a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS).This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes.
Alternative Names CKN1
CSA
Molecular Weight(MW) 44kDa
Sequence 396 amino acids
Database Links
Entrez Gene 1161
SwissProt ID Q13216
Protein Accession NP_000073
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Hela cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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