Western blot
0.2-1 ug/mlPositive Control: MCF7 cell lysate| Product Name | Rabbit anti-APEX1 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | APE, APE1, APEN, APEX, APX, HAP1, REF-1, REF1 |
| Immunogen | The immunogen for anti-APEX1 antibody: synthetic peptide directed towards the N terminal of human APEX1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanPig |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | APEX1 |
|---|---|
| Gene Synonyms | APE APE1 APEN APEX APX HAP1 REF-1 REF1 |
| Gene Full Name | APEX nuclease (multifunctional DNA repair enzyme) 1 |
| Gene Summary | Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. |
| Alternative Names | APE APE1 APEN APEX APX HAP1 REF-1 REF1 |
| Molecular Weight(MW) | 35kDa |
| Sequence | 318 amino acids |
Western blot
0.2-1 ug/mlPositive Control: MCF7 cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
