Western blot
0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: 721_B cell lysate| Product Name | Rabbit anti-CASP1 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ICE, IL1BC, P45 |
| Immunogen | The immunogen for anti-CASP1 antibody: synthetic peptide directed towards the middle region of human CASP1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HorseHuman |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CASP1 |
|---|---|
| Gene Synonyms | ICE IL1BC P45 |
| Gene Full Name | Caspase 1, apoptosis-related cysteine peptidase |
| Gene Summary | This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing of this gene results in five transcript variants encoding distinct isoforms. |
| Alternative Names | ICE IL1BC P45 |
| Molecular Weight(MW) | 10kDa |
| Sequence | 383 amino acids |
Western blot
0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: 721_B cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
