Western blot
0.2-1 ug/mlELISA Titer: 1:312500Positive Control: COLO205 cell lysate| Product Name | Rabbit anti-CASP10 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ALPS2, FLICE2, MCH4 |
| Immunogen | The immunogen for anti-CASP10 antibody: synthetic peptide directed towards the middle region of human CASP10 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CASP10 |
|---|---|
| Gene Synonyms | ALPS2 FLICE2 MCH4 |
| Gene Full Name | Caspase 10, apoptosis-related cysteine peptidase |
| Gene Summary | This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Alternative Names | ALPS2 FLICE2 MCH4 |
| Molecular Weight(MW) | 12kDa |
| Sequence | 479 amino acids |
Western blot
0.2-1 ug/mlELISA Titer: 1:312500Positive Control: COLO205 cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
