Western blot
Host: Rabbit Target Name: CASP10 Sample Tissue: HCT15 Whole Cell lysates Antibody Dilution: 1.0ug/ml| Product Name | Rabbit anti-CASP10 Antibody - c-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ALPS2, FLICE2, MCH4 |
| Immunogen | The immunogen for Anti-CASP10 antibody is: synthetic peptide directed towards the c-terminal region of Human CASP10 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CASP10 |
|---|---|
| Gene Synonyms | ALPS2 FLICE2 MCH4 |
| Gene Full Name | caspase 10, apoptosis-related cysteine peptidase |
| Gene Summary | This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. |
| Alternative Names | ALPS2 FLICE2 MCH4 |
| Molecular Weight(MW) | 57kDa |
| Sequence | 522 amino acids |
Western blot
Host: Rabbit Target Name: CASP10 Sample Tissue: HCT15 Whole Cell lysates Antibody Dilution: 1.0ug/ml| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
