Immunohistochemical
at and mouses, human ovarianWestern blot
0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human brain| Product Name | Rabbit anti-TIMP2 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CSC-21K, Timp-2, Metalloproteinase inhibitor 2, TIMP2, TIMP metallopeptidase inhibitor 2, Tissue inhibitor of metalloproteinases 2, Timp2 |
| Immunogen | The immunogen for anti-TIMP2 antibody: synthetic peptide directed towards the middle region of human TIMP2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| IHC:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHorseHumanMousePigRabbitRatSheep |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TIMP2 |
|---|---|
| Gene Synonyms | CSC-21K |
| Gene Full Name | TIMP metallopeptidase inhibitor 2 |
| Gene Summary | This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. |
| Alternative Names | CSC-21K Timp-2 Metalloproteinase inhibitor 2 TIMP2 TIMP metallopeptidase inhibitor 2 Tissue inhibitor of metalloproteinases 2 Timp2 |
| Molecular Weight(MW) | 22kDa |
| Sequence | 220 amino acids |
Immunohistochemical
at and mouses, human ovarian
Western blot
0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human brain| Application Notes | IHC:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
