| Gene Symbol |
SERPINF2
|
| Gene Synonyms |
A2AP AAP ALPHA-2-PI API PLI |
| Gene Full Name |
Serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 |
| Gene Summary |
This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Alternative Names |
A2AP AAP ALPHA-2-PI API PLI |
| Molecular Weight(MW) |
54kDa |
| Sequence |
491 amino acids |