Western blot
0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human Live| Product Name | Rabbit anti-COCH polyclonal antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | COCH-5B2, COCH5B2, DFNA9 |
| Immunogen | The immunogen for anti-COCH antibody: synthetic peptide directed towards the C terminal of human COCH |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHorseHumanMouseRabbitRatZebra Fish |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | COCH |
|---|---|
| Gene Synonyms | COCH-5B2 COCH5B2 DFNA9 |
| Gene Full Name | Coagulation factor C homolog, cochlin (Limulus polyphemus) |
| Gene Summary | The protein encoded by this gene is highly conserved in human, mouse, and chicken, showing 94% and 79% amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated. |
| Alternative Names | COCH-5B2 COCH5B2 DFNA9 |
| Molecular Weight(MW) | 57kDa |
| Sequence | 550 amino acids |
| Entrez Gene | 1690 |
|---|---|
| SwissProt ID | O43405 |
| Protein Accession | NP_001128530 |
Western blot
0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human Live| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
