Western blot
0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: COLO205 cell lysate| Product Name | Rabbit anti-CMA1 polyclonal antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CYH, MCT1, MGC119890, MGC119891, chymase |
| Immunogen | The immunogen for anti-CMA1 antibody: synthetic peptide directed towards the C terminal of human CMA1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHuman |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CMA1 |
|---|---|
| Gene Synonyms | CYH MCT1 MGC119890 MGC119891 chymase |
| Gene Full Name | Chymase 1, mast cell |
| Gene Summary | CMA1 is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. |
| Alternative Names | CYH MCT1 MGC119890 MGC119891 chymase |
| Molecular Weight(MW) | 27kDa |
| Sequence | 247 amino acids |
Western blot
0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: COLO205 cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
