Western blot
Titration: 1.0 ug/mlPositive Control: Fetal Small Intestine| Product Name | Rabbit anti-CYP2A6 Antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CPA6, CYP2A, CYP2A3, P450C2A, P450PB, CYPIIA6 |
| Immunogen | The immunogen for Anti-CYP2A6 antibody is: synthetic peptide directed towards the C-terminal region of Human CYP2A6 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CYP2A6 |
|---|---|
| Gene Synonyms | CPA6 CYP2A CYP2A3 P450C2A P450PB CYPIIA6 |
| Gene Summary | CYP2A6 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6. |
| Alternative Names | CPA6 CYP2A CYP2A3 P450C2A P450PB CYPIIA6 |
| Molecular Weight(MW) | 56kDa |
| Sequence | 494 amino acids |
Western blot
Titration: 1.0 ug/mlPositive Control: Fetal Small Intestine| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
