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Rabbit anti-CYP21A2 polyclonal antibody - C-terminal region

Catalog Number:OM118340
OM118340
Discount Price
OM118340-100ul
1~2 Week
100ul
OM118340-50ul
50ul
OM118340-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-CYP21A2 polyclonal antibody - C-terminal region
Antibody Type Primary Antibodies
Antigen Alias CA21H, CAH1, CPS1, CYP21, CYP21B, MGC150536, MGC150537, P450c21B
Immunogen The immunogen for anti-CYP21A2 antibody: synthetic peptide directed towards the C terminal of human CYP21A2
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity DogHumanPig
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CYP21A2
Gene Synonyms CA21H
CAH1
CPS1
CYP21
CYP21B
MGC150536
MGC150537
P450c21B
Gene Full Name Cytochrome P450, family 21, subfamily A, polypeptide 2
Gene Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene.
Alternative Names CA21H
CAH1
CPS1
CYP21
CYP21B
MGC150536
MGC150537
P450c21B
Molecular Weight(MW) 56kDa
Sequence 495 amino acids
Database Links
Entrez Gene 1589
SwissProt ID Q16874
Protein Accession NP_000491
Application

Immunohistochemical

Sample Type :Monkey adrenal gland Primary Antibody Dilution : 1:25 Secondary Antibody:Anti-rabbit-HRP Secondary Antibody Dilution: 1:1000 Color/Signal Descriptions:Brown: CYP21A2 Blue: Nucleus Gene Name:CYP21A2 Submitted by:Jonathan Bertin, Endoceutics Inc.

Immunohistochemical

Sample Type :Monkey vagina Primary Antibody Dilution : 1:25 Secondary Antibody:Anti-rabbit-HRP Secondary Antibody Dilution: 1:1000 Color/Signal Descriptions:Brown: CYP21A2 Blue: Nucleus Gene Name:CYP21A2 Submitted by:Jonathan Bertin, Endoceutics Inc.

Western blot

0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human Muscle
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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