Western blot
RabbitTarget Name: FDPSAntibody Dilution: 1.0ug/mlSample Tissue: COLO205 cell lysate| Product Name | Rabbit anti-FDPS polyclonal antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FPPS, FPS |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | FDPS |
|---|---|
| Gene Synonyms | FPPS FPS |
| Gene Full Name | Farnesyl diphosphate synthase |
| Gene Summary | This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Alternative Names | FPPS FPS |
| Molecular Weight(MW) | 38kDa |
| Sequence | 353 amino acids |
| Entrez Gene | 2224 |
|---|---|
| SwissProt ID | Q8WMY2 |
| Protein Accession | NP_001129294 |
Western blot
RabbitTarget Name: FDPSAntibody Dilution: 1.0ug/mlSample Tissue: COLO205 cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
