Immunohistochemistry
Immunohistochemistry with Kidney tissue at an antibody concentration of 5ug/ml using anti-AMACR antibodyWestern blot
AMACR antibody - C-terminal region validated by WB using 721_B cell lysate at 1.0ug/ml.| Product Name | Rabbit anti-AMACR polyclonal antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CBAS4, RACE, RM, AMACRD |
| Immunogen | The immunogen for anti-AMACR antibody: synthetic peptide directed towards the C terminal of human AMACR |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineGuinea PigHumanMousePigRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | AMACR |
|---|---|
| Gene Synonyms | CBAS4 RACE RM AMACRD |
| Gene Full Name | Alpha-methylacyl-CoA racemase |
| Gene Summary | This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. |
| Alternative Names | CBAS4 RACE RM AMACRD |
| Molecular Weight(MW) | 42kDa |
| Sequence | 382 amino acids |
Immunohistochemistry
Immunohistochemistry with Kidney tissue at an antibody concentration of 5ug/ml using anti-AMACR antibody
Western blot
AMACR antibody - C-terminal region validated by WB using 721_B cell lysate at 1.0ug/ml.| Application Notes | WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
