Western blot
Host: Rabbit Target Name: Casp3 Sample Tissue: Mouse Liver lysates Antibody Dilution: 1.0ug/ml| Product Name | Rabbit anti-Casp3 Antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | A830040C14Rik, AC-3, Apopain, CC3, CPP32, Caspase-3, Lice, Yama, mldy |
| Immunogen | The immunogen for Anti-Casp3 antibody is: synthetic peptide directed towards the middle region of Mouse Casp3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | MouseHuman |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Casp3 |
|---|---|
| Gene Synonyms | A830040C14Rik AC-3 Apopain CC3 CPP32 Caspase-3 Lice Yama mldy |
| Gene Full Name | caspase 3, apoptosis-related cysteine peptidase |
| Gene Summary | Casp3 is involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond, cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain, cleaves and activates caspase-6, -7 and -9, triggers cell adhesion in sympathetic neurons through RET cleavage, cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. |
| Alternative Names | A830040C14Rik AC-3 Apopain CC3 CPP32 Caspase-3 Lice Yama mldy |
| Molecular Weight(MW) | 31kDa |
| Sequence | 277 amino acids |
Western blot
Host: Rabbit Target Name: Casp3 Sample Tissue: Mouse Liver lysates Antibody Dilution: 1.0ug/ml| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
