Western blot
Host: Rabbit Target Name: Prnp Sample Tissue: Mouse Kidney lysates Antibody Dilution: 1.0ug/ml| Product Name | Rabbit anti-Prnp Antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AA960666, AI325101, CD230, PrP, PrP , PrPC, PrPSc, Prn-i, Prn-p, Sinc, prP27-30, prP33-35C |
| Immunogen | The immunogen for Anti-Prnp antibody is: synthetic peptide directed towards the middle region of Mouse Prnp |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | MouseHuman |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Prnp |
|---|---|
| Gene Synonyms | AA960666 AI325101 CD230 PrP PrP PrPC PrPSc Prn-i Prn-p Sinc prP27-30 prP33-35C |
| Gene Full Name | prion protein |
| Gene Summary | Prnp may play a role in neuronal development and synaptic plasticity, may be required for neuronal myelin sheath maintenance and may play a role in iron uptake and iron homeostasis. Prnp is a soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. It also provides Cu2+ or ZN2+ for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains. |
| Alternative Names | AA960666 AI325101 CD230 PrP PrP PrPC PrPSc Prn-i Prn-p Sinc prP27-30 prP33-35C |
| Molecular Weight(MW) | 28kDa |
| Sequence | 254 amino acids |
Western blot
Host: Rabbit Target Name: Prnp Sample Tissue: Mouse Kidney lysates Antibody Dilution: 1.0ug/ml| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
