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Rabbit anti-CD207 polyclonal antibody - C-terminal region

Catalog Number:OM119591
OM119591
Discount Price
OM119591-100ul
1~2 Week
100ul
OM119591-50ul
50ul
OM119591-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-CD207 polyclonal antibody - C-terminal region
Antibody Type Primary Antibodies
Antigen Alias CLEC4K
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineGuinea PigHorseMousePigRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CD207
Gene Synonyms CLEC4K
Gene Full Name CD207 molecule, langerin
Gene Summary The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.
Alternative Names CLEC4K
Molecular Weight(MW) 36kDa
Sequence 328 amino acids
Database Links
Entrez Gene 50489
SwissProt ID Q9UJ71
Protein Accession NP_056532
Application

Western blot

Host: Rabbit Target Name: CD207 Sample Tissue: Fetal Kidney Antibody Dilution: 1.0ug/ml
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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