Western blot
Titration: 1.0 ug/mlPositive Control: Placenta| Product Name | Rabbit anti-FCGR3A polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | FCGR3A |
|---|---|
| Gene Synonyms | CD16 CD16A FCG3 FCGR3 FCGRIII FCR-10 FCRIII FCRIIIA IGFR3 |
| Gene Full Name | Fc fragment of IgG, low affinity IIIa, receptor (CD16a) |
| Gene Summary | This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Alternative Names | CD16A FCG3 FCGR3 FCGRIII FCR-10 FCRIII FCRIIIA IGFR3 |
| Molecular Weight(MW) | 27kDa |
| Sequence | 253 amino acids |
| Entrez Gene | 2214 |
|---|---|
| SwissProt ID | P08637 |
| Protein Accession | NP_001121068 |
Western blot
Titration: 1.0 ug/mlPositive Control: Placenta| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
