Immunofluorescence
ImmunofluorescenceWestern blot
Titration: 1.0 ug/mlPositive Control: Fetal Heart| Product Name | Rabbit anti-TFRC polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CD71, TFR, TFR1, TRFR, T9, TR, p90 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TFRC |
|---|---|
| Gene Synonyms | CD71 TFR TFR1 TRFR T9 TR p90 |
| Gene Full Name | Transferrin receptor (p90, CD71) |
| Gene Summary | TFRC is a cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system By similarity. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. |
| Alternative Names | CD71 TFR TFR1 TRFR T9 TR p90 |
| Molecular Weight(MW) | 84kDa |
| Sequence | 760 amino acids |
Immunofluorescence
Immunofluorescence
Western blot
Titration: 1.0 ug/mlPositive Control: Fetal Heart| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
