Western blot
Titration: 1.0 ug/mlPositive Control: 293T Whole Cell| Product Name | Rabbit anti-PANK2 polyclonal antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | C20orf48, FLJ17232, HARP, HSS, MGC15053, NBIA1, PKAN |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogHorseHumanMousePigRabbitRatSheep |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PANK2 |
|---|---|
| Gene Synonyms | C20orf48 FLJ17232 HARP HSS MGC15053 NBIA1 PKAN |
| Gene Full Name | Pantothenate kinase 2 |
| Gene Summary | This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. |
| Alternative Names | C20orf48 FLJ17232 HARP HSS MGC15053 NBIA1 PKAN |
| Molecular Weight(MW) | 47kDa |
| Sequence | 570 amino acids |
Western blot
Titration: 1.0 ug/mlPositive Control: 293T Whole Cell| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
