Western blot
Titration: 1.0 ug/mlPositive Control: Fetal Live| Product Name | Rabbit anti-ITGA2B polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CD41, CD41B, GP2B, GPIIb, GTA, HPA3, GT, BDPLT2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | DogGuinea PigHorseMousePigRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ITGA2B |
|---|---|
| Gene Synonyms | CD41 CD41B GP2B GPIIb GTA HPA3 GT BDPLT2 |
| Gene Full Name | Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| Gene Summary | ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. |
| Alternative Names | CD41 CD41B GP2B GPIIb GTA HPA3 GT BDPLT2 |
| Molecular Weight(MW) | 16kDa |
| Sequence | 1039 amino acids |
Western blot
Titration: 1.0 ug/mlPositive Control: Fetal Live| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
