Western blot
Titration: 1.0 ug/mlPositive Control: U937 Whole Cell| Product Name | Rabbit anti-LIMS1 Antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PINCH, PINCH1 |
| Immunogen | The immunogen for Anti-LIMS1 antibody is: synthetic peptide directed towards the middle region of Human LIMS1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | LIMS1 |
|---|---|
| Gene Synonyms | PINCH PINCH1 |
| Gene Summary | The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. |
| Alternative Names | PINCH PINCH1 |
| Molecular Weight(MW) | 44kDa |
| Sequence | 387 amino acids |
| Entrez Gene | 3987 |
|---|---|
| SwissProt ID | B7Z7R3 |
| Protein Accession | NP_001180414 |
Western blot
Titration: 1.0 ug/mlPositive Control: U937 Whole Cell| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
