| Product Name | Rabbit anti-CFLAR polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLIP, I-FLICE, MRIT, USURPIN, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS, FLAME1 |
| Immunogen | The immunogen for anti-CFLAR antibody: synthetic peptide directed towards the middle region of human CFLAR |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CFLAR |
|---|---|
| Gene Synonyms | CASH CASP8AP1 CLARP Casper FLAME FLAME-1 FLIP I-FLICE MRIT USURPIN c-FLIP c-FLIPL c-FLIPR c-FLIPS FLAME1 |
| Gene Full Name | CASP8 and FADD-like apoptosis regulator |
| Gene Summary | CFLAR belongs to the peptidase C14A family. It is a apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. The protein acts as an inhibitor of TNFRSF6 mediated apoptosis. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. CFLAR lacks enzymatic (caspase) activity. |
| Alternative Names | CASH CASP8AP1 CLARP Casper FLAME FLAME-1 FLIP I-FLICE MRIT USURPIN c-FLIP c-FLIPL c-FLIPR c-FLIPS FLAME1 |
| Molecular Weight(MW) | 55kDa |
| Sequence | 480 amino acids |
| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
