| Product Name | Rabbit anti-CDKN2B polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | P15, MTS2, TP15, CDK4I, INK4B, p15INK4b |
| Immunogen | The immunogen for anti-CDKN2B antibody: synthetic peptide directed towards the middle region of human CDKN2B |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | DogGuinea PigMousePigRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CDKN2B |
|---|---|
| Gene Synonyms | P15 MTS2 TP15 CDK4I INK4B p15INK4b |
| Gene Full Name | Cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) |
| Gene Summary | CDKN2B's gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. CDKN2B is a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. |
| Alternative Names | P15 MTS2 TP15 CDK4I INK4B p15INK4b |
| Molecular Weight(MW) | 15kDa |
| Sequence | 138 amino acids |
| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
