| Product Name | Rabbit anti-MAPK14 polyclonal antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RK, p38, CSBP, EXIP, Mxi2, CSBP1, CSBP2, CSPB1, PRKM14, PRKM15, SAPK2A, p38ALPHA |
| Immunogen | The immunogen for anti-MAPK14 antibody: synthetic peptide directed towards the C terminal of human MAPK14 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineHorseHumanMousePigRabbitRatSheep |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | MAPK14 |
|---|---|
| Gene Synonyms | RK p38 CSBP EXIP Mxi2 CSBP1 CSBP2 CSPB1 PRKM14 PRKM15 SAPK2A p38ALPHA |
| Gene Full Name | Mitogen-activated protein kinase 14 |
| Gene Summary | MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| Alternative Names | RK p38 CSBP EXIP Mxi2 CSBP1 CSBP2 CSPB1 PRKM14 PRKM15 SAPK2A p38ALPHA |
| Molecular Weight(MW) | 41kDa |
| Sequence | 360 amino acids |
| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
