| Product Name | CCL2 antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-CCL2 antibody: synthetic peptide directed towards the middle region of human CCL2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| Species Reactivity | DogHuman |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CCL2 |
|---|---|
| Gene Synonyms | GDCF-2 GDCF-2 HC11 HC11 HSMCR30 MCAF MCP-1 MCP1 MGC9434 SCYA2 SMC-CF |
| Gene Full Name | Chemokine (C-C motif) ligand 2 |
| Gene Summary | CCL2 is a chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. CCL2 augments monocyte anti-tumor activity. CCL2 has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. CCL2 may be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Alternative Names | GDCF-2 GDCF-2 HC11 HC11 HSMCR30 MCAF MCP-1 MCP1 MGC9434 SCYA2 SMC-CF |
| Molecular Weight(MW) | 11kDa |
| Sequence | 99 amino acids |
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
