Application
MBD4 Antibody (Center) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the MBD4 antibody detected the MBD4 protein (arrow).| Product Name | MBD4 (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MBD4; MED1; Methyl-CpG-binding domain protein 4; Methyl-CpG-binding endonuclease 1; Methyl-CpG-binding protein MBD4; Mismatch-specific DNA N-glycosylase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MED1 |
|---|---|
| Alternative Names | MBD4 MED1 Methyl-CpG-binding domain protein 4 Methyl-CpG-binding endonuclease 1 Methyl-CpG-binding protein MBD4 Mismatch-specific DNA N-glycosylase |
| Molecular Weight(MW) | 66051 Da |
| Function | Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein |
| Tissue Specificity | This MBD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-351 amino acids from the Central region of human MBD4. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 8930 |
|---|---|
| Nucleotide Accession | NP_003916.1 |
Application
MBD4 Antibody (Center) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the MBD4 antibody detected the MBD4 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
