MED16 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the MED16 antibody detected the MED16 protein (arrow).
MED16; DRIP92; THRAP5; Mediator of RNA polymerase II transcription subunit 16; Mediator complex subunit 16; Thyroid hormone receptor-associated protein 5; Thyroid hormone receptor-associated protein complex 95 kDa component; Vitamin D3 receptor-interacting
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
DRIP92 THRAP5
Alternative Names
MED16 DRIP92 THRAP5 Mediator of RNA polymerase II transcription subunit 16 Mediator complex subunit 16 Thyroid hormone receptor-associated protein 5 Thyroid hormone receptor-associated protein complex 95 kDa component Vitamin D3 receptor-interacting
Molecular Weight(MW)
96793 Da
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors
Tissue Specificity
This MED16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-281 amino acids from the Central region of human MED16.
MED16 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the MED16 antibody detected the MED16 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.