Application
A. Western blot analysis on A) fetal brain , B) human heart, and C) HeLa lysate using anti-MEF2A RabMAb (Cat. #AJ1467a), dilution 1:10,000.Application
B. Immunohistochemical analysis of paraffin-embedded human kidney using anti-MEF2a RabMAb (Cat. #AJ1467a).| Product Name | MEF2A Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP1706Y |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:1000~5000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MEF2 |
|---|---|
| Molecular Weight(MW) | 54811 Da |
| Function | Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle- specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation |
| Tissue Specificity | Isoform MEF2 and isoform MEFA are expressed only in skeletal and cardiac muscle and in the brain. Isoform RSRFC4 and isoform RSRFC9 are expressed in all tissues examined |
| Cellular Localization | Nucleus. |
| Entrez Gene | 4205 |
|---|
Application
A. Western blot analysis on A) fetal brain , B) human heart, and C) HeLa lysate using anti-MEF2A RabMAb (Cat. #AJ1467a), dilution 1:10,000.
Application
B. Immunohistochemical analysis of paraffin-embedded human kidney using anti-MEF2a RabMAb (Cat. #AJ1467a).| Application Notes | WB:1:1000~5000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
