Application
A. Western blot analysis on recombinant protein using anti-MMP-12 RabMAb (Cat. #AJ1493a), dilution 1:2000Application
B. Immunohistochemical staining of paraffin-embedded human breast carcinoma using anti-MMP-12 RabMAb (Cat. #AJ1493a).Application
C. Immunofluorescent staining of HeLa cells using anti-MMP-12 RabMAb (Cat. #AJ1493a).| Product Name | MMP-12 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MMP12, HME, Macrophage metalloelastase, Macrophage elastase |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP1261Y |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | HME |
|---|---|
| Alternative Names | MMP12 HME Macrophage metalloelastase Macrophage elastase |
| Molecular Weight(MW) | 54002 Da |
| Function | May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3 |
| Tissue Specificity | Found in alveolar macrophages but not in peripheral blood monocytes |
| Cellular Localization | Secreted, extracellular space, extracellular matrix (Probable) |
| Entrez Gene | 4321 |
|---|
Application
A. Western blot analysis on recombinant protein using anti-MMP-12 RabMAb (Cat. #AJ1493a), dilution 1:2000
Application
B. Immunohistochemical staining of paraffin-embedded human breast carcinoma using anti-MMP-12 RabMAb (Cat. #AJ1493a).
Application
C. Immunofluorescent staining of HeLa cells using anti-MMP-12 RabMAb (Cat. #AJ1493a).| Application Notes | WB:1:500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
