Application
Western blot analysis of MXD4 antibody (C-term) (Cat.# AP6539b) in Y79 cell line lysates (35ug/lane). MXD4 (arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human Lung carcinoma reacted with MXD4 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | MXD4 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MXD4; BHLHC12; MAD4; Max dimerization protein 4; Class C basic helix-loop-helix protein 12; Max-associated protein 4; Max-interacting transcriptional repressor MAD4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BHLHC12 MAD4 |
|---|---|
| Alternative Names | MXD4 BHLHC12 MAD4 Max dimerization protein 4 Class C basic helix-loop-helix protein 12 Max-associated protein 4 Max-interacting transcriptional repressor MAD4 |
| Molecular Weight(MW) | 23528 Da |
| Function | Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation (By similarity) |
| Tissue Specificity | This MXD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142~171 amino acids from the C-terminal region of human MXD4. |
| Cellular Localization | Nucleus (By similarity). |
| Entrez Gene | 10608 |
|---|
Application
Western blot analysis of MXD4 antibody (C-term) (Cat.# AP6539b) in Y79 cell line lysates (35ug/lane). MXD4 (arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human Lung carcinoma reacted with MXD4 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
