Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival
Tissue Specificity
A synthetic peptide corresponding to residues near the C-terminus of human NGF-β was used as an immunogen.