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NKX6-1 Antibody (C-term)

Catalog Number:OM215408
OM215408
Discount Price
OM215408-100ul
1~2 Week
100ul
OM215408-50ul
50ul
OM215408-20ul
20ul
1~2 Week
Product Profile
Product Name NKX6-1 Antibody (C-term)
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WB
WB:1:100~500
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms NKX6A
Alternative Names NKX6-1
NKX6A
Homeobox protein Nkx-6.1
Homeobox protein NK-6 homolog A
Molecular Weight(MW) 37849 Da
Function Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes Involved in transcriptional regulation in islet beta cells. Binds to the insulin promoter and is involved in regulation of the insulin gene. Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals (By similarity)
Tissue Specificity Pancreatic beta cells.
Cellular Localization Nucleus (Probable).
Database Links
Entrez Gene 4825
Nucleotide Accession NP_006159.2
Application

Application

NKX6-1 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the NKX6-1 antibody detected the NKX6-1 protein (arrow).
Application Notes WB:1:100~500
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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