Application
p130cas Antibody (Center Y224) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the p130cas antibody detected the p130cas protein (arrow).Application
p130cas Antibody (Center Y224) flow cytometric analysis of Neuro-2a cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.| Product Name | p130cas Antibody (Center Y224) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BCAR1; CAS; CASS1; CRKAS; Breast cancer anti-estrogen resistance protein 1; CRK-associated substrate; Cas scaffolding protein family member 1; p130cas |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CAS CASS1 CRKAS |
|---|---|
| Alternative Names | BCAR1 CAS CASS1 CRKAS Breast cancer anti-estrogen resistance protein 1 CRK-associated substrate Cas scaffolding protein family member 1 p130cas |
| Molecular Weight(MW) | 93372 Da |
| Function | Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells |
| Tissue Specificity | Widely expressed with an abundant expression in the testis. Low level of expression seen in the liver, thymus, and peripheral blood leukocytes. The protein has been detected in a B-cell line |
| Cellular Localization | Cell junction, focal adhesion. Cytoplasm. Note=Unphosphorylated form localizes in the cytoplasm and can move to the membrane upon tyrosine phosphorylation (By similarity) |
Application
p130cas Antibody (Center Y224) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the p130cas antibody detected the p130cas protein (arrow).
Application
p130cas Antibody (Center Y224) flow cytometric analysis of Neuro-2a cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
