Application
A. Western blot analysis on HeLa (A) untreated (B) treated with dexamethasone using anti-p57/KIP2 RabMAb (Cat. #AJ1574a)| Product Name | p57/KIP2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP2516 |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:1000~10000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIP2 |
|---|---|
| Molecular Weight(MW) | 32177 Da |
| Function | Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non- proliferative state throughout life |
| Tissue Specificity | Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. Expressed in the eye. High levels are seen in the placenta while low levels are seen in the liver |
| Cellular Localization | Nucleus (By similarity). |
| Entrez Gene | 1028 |
|---|
Application
A. Western blot analysis on HeLa (A) untreated (B) treated with dexamethasone using anti-p57/KIP2 RabMAb (Cat. #AJ1574a)| Application Notes | WB:1:1000~10000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
