Application
A. Western blot analysis of anti p73 RabMAb (Cat. #AJ1578a). dilution 1: 2,000 A: Hela B: Jurkat C: NIH 3T3Application
B. Immunohistochemical analysis of paraffin-embedded human urinary bladder carcinoma using anti-p73 RabMAb RabMAb (Cat. #AJ1578a).| Product Name | p73 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TP73, P73, Tumor protein p73, p53-like transcription factor;p53-related protein |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP436Y |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:1000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | P73 |
|---|---|
| Alternative Names | TP73 P73 Tumor protein p73 p53-like transcription factor p53-related protein |
| Molecular Weight(MW) | 69623 Da |
| Function | Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein |
| Tissue Specificity | Expressed in striatal neurons of patients with Huntington disease (at protein level). Brain, kidney, placenta, colon, heart, liver, spleen, skeletal muscle, prostate, thymus and pancreas. Highly expressed in fetal tissue |
| Cellular Localization | Nucleus. Cytoplasm. Note=Accumulates in the nucleus in response to DNA damage |
| Entrez Gene | 7161 |
|---|
Application
A. Western blot analysis of anti p73 RabMAb (Cat. #AJ1578a). dilution 1: 2,000 A: Hela B: Jurkat C: NIH 3T3
Application
B. Immunohistochemical analysis of paraffin-embedded human urinary bladder carcinoma using anti-p73 RabMAb RabMAb (Cat. #AJ1578a).| Application Notes | WB:1:1000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
