Application
PCAF Antibody (C-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the PCAF antibody detected the PCAF protein (arrow).| Product Name | PCAF Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KAT2B; PCAF; Histone acetyltransferase KAT2B; Histone acetyltransferase PCAF; Lysine acetyltransferase 2B; P300/CBP-associated factor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | PCAF |
|---|---|
| Alternative Names | KAT2B PCAF Histone acetyltransferase KAT2B Histone acetyltransferase PCAF Lysine acetyltransferase 2B P300/CBP-associated factor |
| Molecular Weight(MW) | 93013 Da |
| Function | Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes |
| Tissue Specificity | Ubiquitously expressed but most abundant in heart and skeletal muscle |
| Cellular Localization | Nucleus (By similarity). |
| Entrez Gene | 8850 |
|---|---|
| Nucleotide Accession | NP_003875.3 |
Application
PCAF Antibody (C-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the PCAF antibody detected the PCAF protein (arrow).| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
