Application
Western blot analysis of PCQAP Antibody (Center) in 293 cell line lysates (35ug/lane). PCQAP (arrow) was detected using the purified Pab.| Product Name | PCQAP Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MED15; ARC105; CTG7A; PCQAP; TIG1; TNRC7; Mediator of RNA polymerase II transcription subunit 15; Activator-recruited cofactor 105 kDa component; CTG repeat protein 7a; Mediator complex subunit 15; Positive cofactor 2 glutamine/Q-rich-associated protein; T |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ARC105 CTG7A PCQAP TIG1 TNRC7 |
|---|---|
| Alternative Names | MED15 ARC105 CTG7A PCQAP TIG1 TNRC7 Mediator of RNA polymerase II transcription subunit 15 Activator-recruited cofactor 105 kDa component CTG repeat protein 7a Mediator complex subunit 15 Positive cofactor 2 glutamine/Q-rich-associated protein T |
| Molecular Weight(MW) | 86753 Da |
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol-dependent gene regulation. Positively regulates the Nodal signaling pathway |
| Tissue Specificity | Expressed in all tissues examined, including heart, brain, lung, spleen, thymus, pancreas, blood leukocyte and placenta. However, the level of expression varied, with highest expression in the placenta and peripheral blood and lowest in the pancreas and kidney |
| Cellular Localization | Cytoplasm. Nucleus. |
| Entrez Gene | 51586 |
|---|
Application
Western blot analysis of PCQAP Antibody (Center) in 293 cell line lysates (35ug/lane). PCQAP (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
