Application
PEX19 Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the PEX19 antibody detected the PEX19 protein (arrow).| Product Name | PEX19 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PEX19; HK33; PXF; Peroxisomal biogenesis factor 19; 33 kDa housekeeping protein; Peroxin-19; Peroxisomal farnesylated protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | HK33 PXF |
|---|---|
| Alternative Names | PEX19 HK33 PXF Peroxisomal biogenesis factor 19 33 kDa housekeeping protein Peroxin-19 Peroxisomal farnesylated protein |
| Molecular Weight(MW) | 32807 Da |
| Function | Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3 Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53 |
| Tissue Specificity | Ubiquitously expressed. Isoform 1 is strongly predominant in all tissues except in utero where isoform 2 is the main form |
| Cellular Localization | Cytoplasm. Peroxisome membrane; Lipid- anchor; Cytoplasmic side. Note=Mainly cytoplasmic. Some fraction membrane-associated to the outer surface of peroxisomes |
| Entrez Gene | 5824 |
|---|---|
| Nucleotide Accession | NP_001180573.1 NP_002848.1 |
Application
PEX19 Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the PEX19 antibody detected the PEX19 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
