Application
Dot blot analysis of anti-Phospho-IGFBP-3-pS183 Pab on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.| Product Name | Phospho-IGFBP-3-pS183 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification | p-S183 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | DB |
| DB:1:500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | IBP3 |
|---|---|
| Alternative Names | IGFBP3 IBP3 Insulin-like growth factor-binding protein 3 |
| Molecular Weight(MW) | 31674 Da |
| Function | IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R |
| Tissue Specificity | Expressed by most tissues. Present in plasma. |
| Cellular Localization | Secreted. |
| Entrez Gene | 3486 |
|---|
Application
Dot blot analysis of anti-Phospho-IGFBP-3-pS183 Pab on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.| Application Notes | DB:1:500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
