Application
Western blot analysis on (A) K562 (B) 293T (C) HUVEC (D) HepG2 cell lysates and (E) Fetal Brain tissue lysates using anti-Plexin-A1 RabMAb (Cat. #AJ1637a).| Product Name | Plexin-A1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PLXNA1, NOV, PLXN1, Plexin-A1, Semaphorin receptor NOV |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EPR3449 |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NOV PLXN1 |
|---|---|
| Alternative Names | PLXNA1 NOV PLXN1 Plexin-A1 Semaphorin receptor NOV |
| Molecular Weight(MW) | 211067 Da |
| Function | Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down- stream signaling events in the cytoplasm (By similarity) |
| Tissue Specificity | Detected in fetal brain, lung, liver and kidney |
| Cellular Localization | Cell membrane (Probable); Single-pass type I membrane protein (By similarity) |
| Entrez Gene | 5361 |
|---|
Application
Western blot analysis on (A) K562 (B) 293T (C) HUVEC (D) HepG2 cell lysates and (E) Fetal Brain tissue lysates using anti-Plexin-A1 RabMAb (Cat. #AJ1637a).| Application Notes | WB:1:500~1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
