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PTH2R Antibody (Center)

Catalog Number:OM219022
OM219022
Discount Price
OM219022-100ul
1~2 Week
100ul
OM219022-50ul
50ul
OM219022-20ul
20ul
1~2 Week
Product Profile
Product Name PTH2R Antibody (Center)
Antibody Type Primary Antibodies
Antigen Alias PTH2R; PTHR2; Parathyroid hormone 2 receptor
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms PTHR2
Alternative Names PTH2R
PTHR2
Parathyroid hormone 2 receptor
Molecular Weight(MW) 62236 Da
Function This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor (By similarity)
Tissue Specificity Expressed abundantly in brain and pancreas. Also expressed in the testis
Cellular Localization Cell membrane; Multi-pass membrane protein.
Database Links
Entrez Gene 5746
Application

Application

Western blot analysis of PTH2R Antibody (Center) in mouse testis tissue lysates (35ug/lane). PTH2R (arrow) was detected using the purified Pab.

Application

Formalin-fixed and paraffin-embedded human brain tissue reacted with PTH2R Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Application

PTH2R Antibody (Center) flow cytometric analysis of HepG2 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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