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RANGAP1 Antibody (N-term)

Catalog Number:OM219441
OM219441
Discount Price
OM219441-100ul
1~2 Week
100ul
OM219441-50ul
50ul
OM219441-20ul
20ul
1~2 Week
Product Profile
Product Name RANGAP1 Antibody (N-term)
Antibody Type Primary Antibodies
Antigen Alias RANGAP1; KIAA1835; SD; Ran GTPase-activating protein 1
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms KIAA1835
SD
Alternative Names RANGAP1
KIAA1835
SD
Ran GTPase-activating protein 1
Molecular Weight(MW) 63542 Da
Function GTPase activator for the nuclear Ras-related regulatory protein Ran, converting it to the putatively inactive GDP-bound state
Tissue Specificity Highly expressed in brain, thymus and testis.
Cellular Localization Cytoplasm. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Chromosome, centromere, kinetochore (By similarity). Cytoplasm, cytoskeleton, spindle pole (By similarity). Note=Cytoplasmic during interphase. Targeted to the nuclear rim after sumoylation. During mitosis, associates with mitotic spindles. Association with kinetochores appears soon after nuclear envelope breakdown and persists until late anaphase Mitotic location also requires sumoylation
Database Links
Entrez Gene 5905
Nucleotide Accession NP_002874.1
Application

Application

RANGAP1 Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the RANGAP1 antibody detected the RANGAP1 protein (arrow).

Application

Western blot analysis of RANGAP1 (arrow) using rabbit polyclonal RANGAP1 Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the RANGAP1 gene.

Application

RANGAP1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RANGAP1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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