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S adenosylhomocysteine hydrolase (ACHY) Antibody (C-term)

Catalog Number:OM220395
OM220395
Discount Price
OM220395-100ul
1~2 Week
100ul
OM220395-50ul
50ul
OM220395-20ul
20ul
1~2 Week
Product Profile
Product Name S adenosylhomocysteine hydrolase (ACHY) Antibody (C-term)
Antibody Type Primary Antibodies
Antigen Alias AHCY; SAHH; Adenosylhomocysteinase; S-adenosyl-L-homocysteine hydrolase
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:50~100 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms SAHH
Alternative Names AHCY
SAHH
Adenosylhomocysteinase
S-adenosyl-L-homocysteine hydrolase
Molecular Weight(MW) 47716 Da
Function Adenosylhomocysteine is a competitive inhibitor of S- adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine
Tissue Specificity This ACHY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 403~432 amino acids from the C-terminal region of human AHCY.
Cellular Localization Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Database Links
Entrez Gene 191
Application

Application

Western blot analysis of anti-AHCY Antibody (C-term) in HepG2 cell line lysates (35ug/lane). AHCY(arrow) was detected using the purified Pab (1:60 dilution).

Application

Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with AHCY antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Application Notes WB:1:50~100 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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