Application
S1PR5 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the S1PR5 antibody detected the S1PR5 protein (arrow).| Product Name | S1PR5 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | S1PR5; EDG8; Sphingosine 1-phosphate receptor 5; Endothelial differentiation G-protein-coupled receptor 8; Sphingosine 1-phosphate receptor Edg-8 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | EDG8 |
|---|---|
| Alternative Names | S1PR5 EDG8 Sphingosine 1-phosphate receptor 5 Endothelial differentiation G-protein-coupled receptor 8 Sphingosine 1-phosphate receptor Edg-8 |
| Molecular Weight(MW) | 41775 Da |
| Function | Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells |
| Tissue Specificity | Widely expressed in the brain, most prominently in the corpus callosum, which is predominantly white matter. Detected in spleen, peripheral blood leukocytes, placenta, lung, aorta and fetal spleen. Low-level signal detected in many tissue extracts. Overexpressed in leukemic large granular lymphocytes. Isoform 1 is predominantly expressed in peripheral tissues. Isoform 2 is expressed in brain, spleen and peripheral blood leukocytes |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. |
| Entrez Gene | 53637 |
|---|---|
| Nucleotide Accession | NP_001159687.1 NP_110387.1 |
Application
S1PR5 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the S1PR5 antibody detected the S1PR5 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
