Application
SCARB1 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the SCARB1 antibody detected the SCARB1 protein (arrow).| Product Name | SCARB1 (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SCARB1; CD36L1; CLA1; Scavenger receptor class B member 1; CD36 and LIMPII analogous 1; CD36 antigen-like 1; Collagen type I receptor, thrombospondin receptor-like 1; SR-BI; CD_antigen=CD36 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CD36L1 CLA1 |
|---|---|
| Alternative Names | SCARB1 CD36L1 CLA1 Scavenger receptor class B member 1 CD36 and LIMPII analogous 1 CD36 antigen-like 1 Collagen type I receptor thrombospondin receptor-like 1 SR-BI CD_antigen=CD36 |
| Molecular Weight(MW) | 60878 Da |
| Function | Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. Plays an important role in the uptake of HDL cholesteryl ester (By similarity) |
| Tissue Specificity | Widely expressed. |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. Membrane, caveola; Multi-pass membrane protein. Note=Predominantly localized to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae |
| Entrez Gene | 949 |
|---|---|
| Nucleotide Accession | NP_005496.4 |
Application
SCARB1 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the SCARB1 antibody detected the SCARB1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
