Application
SF3B3 Antibody (C-term) western blot analysis in MDA-MB453,Jurkat cell line lysates (35ug/lane).This demonstrates the SF3B3 antibody detected the SF3B3 protein (arrow).| Product Name | SF3B3 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SF3B3; KIAA0017; SAP130; Splicing factor 3B subunit 3; Pre-mRNA-splicing factor SF3b 130 kDa subunit; STAF130; Spliceosome-associated protein 130 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0017 SAP130 |
|---|---|
| Alternative Names | SF3B3 KIAA0017 SAP130 Splicing factor 3B subunit 3 Pre-mRNA-splicing factor SF3b 130 kDa subunit STAF130 Spliceosome-associated protein 130 |
| Molecular Weight(MW) | 135577 Da |
| Function | Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron |
| Tissue Specificity | This SF3B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1053-1082 amino acids from the C-terminal region of human SF3B3. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 23450 |
|---|---|
| Nucleotide Accession | NP_036558.3 |
Application
SF3B3 Antibody (C-term) western blot analysis in MDA-MB453,Jurkat cell line lysates (35ug/lane).This demonstrates the SF3B3 antibody detected the SF3B3 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
