Application
SH2D1A Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SH2D1A antibody detected the SH2D1A protein (arrow).| Product Name | SH2D1A Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SH2D1A; DSHP; SAP; SH2 domain-containing protein 1A; Duncan disease SH2-protein; Signaling lymphocytic activation molecule-associated protein; T-cell signal transduction molecule SAP |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | DSHP SAP |
|---|---|
| Alternative Names | SH2D1A DSHP SAP SH2 domain-containing protein 1A Duncan disease SH2-protein Signaling lymphocytic activation molecule-associated protein T-cell signal transduction molecule SAP |
| Molecular Weight(MW) | 14187 Da |
| Function | Inhibitor of the SLAM self-association. Acts by blocking recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to a docking site in the SLAM cytoplasmic region Mediates interaction between FYN and SLAMF1. May also regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3 |
| Tissue Specificity | Expressed at a high level in thymus and lung, with a lower level of expression in spleen and liver. Expressed in peripheral blood leukocytes, including T lymphocytes. Tends to be expressed at lower levels in peripheral blood leukocytes in patients with rheumatoid arthritis |
| Cellular Localization | Cytoplasm (Probable). |
| Entrez Gene | 4068 |
|---|---|
| Nucleotide Accession | NP_002342.1 |
Application
SH2D1A Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SH2D1A antibody detected the SH2D1A protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
